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Premier’s Commitment and Solution to Support Antimicrobial Stewardship

In September 2018, Premier announced its commitment opens in a new tab to the Centers for Disease Control and Prevention’s (CDC’s) Antibiotic Resistance (AMR) Challenge. opens in a new tab Premier has helped hundreds of healthcare organizations implement successful antimicrobial stewardship programs that strengthen surveillance, reduce inappropriate use and prevent the spread of resistant infections.

On Sept. 23, 2019, the CDC concluded the year-long challenge and celebrated its successes. Premier was specifically featured by HHS Secretary Azar as an example of demonstratable improvements in its commitment to reduce antimicrobial resistance (AMR) through applied AMS at the conclusion of the CDC’s yearlong AMR Challenge in September 2019 (link opens in a new tab).

Using an array of data-driven solutions, research and educational services, and performance improvement collaboratives, Premier participated in actionable, impactful, measurable and timely initiatives to further combat AMR. Specifically, Premier acted on three of the AMR Challenge’s core challenge areas: tracking and data, infection prevention and control, and antibiotic use. Premier worked with its members to enable increased reporting of antimicrobial usage and resistance (AUR) data; leverage our deep analytics to benchmark and understand usage patterns; and apply our collaborative methodology to target, implement and measure performance improvement efforts.

Leading experts from the public and private sectors released an urgently needed tool to help acute-care hospitals implement strategies to promote appropriate, safe use of antibiotics. Antibiotic Stewardship in Acute Care: A Practical Playbook opens in a new tab was released by The National Quality Forum (NQF) and the Centers for Disease Control and Prevention (CDC) and developed by more than 25 experts and organizations, including Premier.

Premier and its alliance members recognize the critical need for antimicrobial stewardship (AMS) and are committed to reducing antibiotic resistance. Antimicrobial stewardship encompasses appropriate use of antimicrobial agents that inhibit or kill micro-organisms, including bacteria, viruses and fungi – antibiotics that act against bacteria are the most common. Premier, along with several its members, joined 150 major stakeholders in the June 2, 2015, White House Forum on Antibiotic Stewardship to share commitments to implement initiatives to slow the emergence of resistant bacteria and prevent the spread of resistant infections. “Commitments also included improvements in antibiotic use and prescribing.”

Premier focused its efforts on the first two goals of the National Action Plan for Combating Antibiotic-Resistant Bacteria opens in a new tab:

    1. Slowing emergence of resistant bacteria and preventing the spread of resistant infections, and
    2. Strengthening national surveillance efforts to combat resistance. Premier continues to align its antimicrobial stewardship offerings to achieve the outcomes related to these goals.


Research by Premier and the CDC published in September 2014 found that 78 percent (394) of hospitals studied had evidence of at least of 23 potentially unnecessary or redundant combinations of antibiotics being prescribed for two or more days. In addition to potential harm and drug resistance, these cases represented more than $13 million in avoidable healthcare costs to antimicrobial drugs.

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